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Address
P.O.
Box 647
Gilbertsville,
PA 19525
Phone
610-705-0828
Fax
610-705-0810
Email
gposte@healthtechnetwork.com
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PUBLISHED WORKS
Dr. George Poste
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1.
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Poste, G. (1970)
Increased growth of viruses in lymphocytes treated with heterologous
antilymphocyte serum. Transplantation
10, 106-115
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2.
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Poste, G. (1970)
Virus-induced polykaryocytosis and the mechanism of cell fusion. In: Advances in Virus Research (eds. F.B. Bang and K.
Smith) Vol. 16, pp. 303-356, Academic Press, New York.
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3.
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Poste, G. (1970)
Cell surface changes in virus-induced cell fusion. 1. The importance of
microvilli. Microbios
2, 227-239.
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4.
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Poste, G. (1970) The
measurement of cell surface glycoprotein coat materials by ellipsometry. 1.
The techniques. Cytobios
2, 233-241.
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5.
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Poste, G. and
Greenham, L. W. (1970) The measurement of cell surface glycoprotein coat
materials by ellipsometry. 2.
Variation in coat thickness with cell type, tissue organization and culture
conditions. Cytobios 2,
243-256.
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6.
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Poste, G. (1970)
Mixed-culture polykaryocytosis:
A new form of cellular recognition behaviour. Life Sciences 9, 459-463.
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7.
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Greenham, L. W. and Poste,
G. (1971) The role of lysosomes in virus-induced cell fusion. 1. Cytochemical studies. Microbios 3, 97-104.
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8.
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Poste, G. (1971) The
role of lysosomes in virus-induced cell fusion. 2.
Modification of the cell surface. Microbios 3, 105-112.
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9.
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Poste, G. (1971)
Cell surface changes in virus-induced cell fusion. 2. Changes in cell coat
thickness. Microbios 3,
55-61.
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10.
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Poste, G. and Reeve,
P. (1971) Formation of hybrid cells and heterokaryons by fusion of
enucleated and nucleated cells.
Nature New Biology 229, 123-125.
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11.
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Poste, G. and
Greenham, L. W. (1971) The measurement of cell surface glycoprotein coat
materials by ellipsometry. 3.
Synthesis of coat materials. Cytobios
3, 5-15.
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12.
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Poste, G. (1971)
Tissue dissociation with proteolytic enzymes: Adsorption and activity of enzymes at the cell
surface. Exp. Cell Res.
65, 359-367.
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13.
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Poste, G. (1971)
Sub-lethal autolysis: Modification
of the cell periphery by lysosomal enzymes. Exp. Cell Res. 67, 11-16.
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14.
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Reeve, P. and Poste,
G. (1971) Cell fusion by Newcastle disease virus in the absence of RNA
synthesis. Nature New
Biology 229, 1957-1958.
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15.
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Poste, G. and
Allison, A.C. (1971) The membrane fusion reaction: A theory. J. Theor. Biol. 32, 165-184.
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16.
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Reeve, P. and Poste,
G. (1971) Studies on the cytopathogenicity of Newcastle disease virus. I. Relation between virulence,
polykaryocytosis and plaque size.
J. Gen. Virol. 11, 17-24.
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17.
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Reeve, P.,
Alexander, D.J., Pope, G. and Poste, G. (1971) Studies on the cytopathic
effects of Newcastle disease virus.
J. Gen. Virol. 11, 25-34
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18.
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Poste, G. and King,
N. (1971) Isolation of a herpesvirus from the canine genital tract: Association with infertility,
abortion and stillbirths. Veterinary
Record 88, 229-233.
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19.
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Poste, G. (1971) The
growth and cytopathogenicity of virulent and attenuated strains of canine
distemper virus in dog and ferret macrophages. J. Comp. Path. 81, 49-54.
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20.
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Poste, G. and Reese,
P. (1972) Inhibition of virus-induced cell fusion by local anaesthetics and
phenothiazine tranquillizers. J.
Gen. Virol. 16, 21-28.
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21.
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Poste, G. and Reeve,
P. (1972) Inhibition of cell fusion by local anesthetics and
tranquilizers. Exp. Cell
Res. 72, 556-560.
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22.
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Mallucci, L., Poste,
G. and Wells, V. (1972) Synthesis of cell coat in normal and transformed
cells. Nature New Biology
235, 222-223.
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23.
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Poste, G. and Reeve,
P. (1972) Agglutination of normal cells by plant lectins following
infection with nononcogenic viruses.
Nature New Biology 237, 113-114.
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24.
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Poste, G. (1972)
Enucleation of mammalian cells by cytochalasin B. I. Characterization of anucleate cells. Exp. Cell Res. 73, 273-286.
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25.
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Apostolov, K. and
Poste, G. (1972) Interaction of Sendai virus with human erythrocytes: A system for the study of membrane
fusion. Microbios 6,
247-261.
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26.
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Reeve, P., Poste,
G., Alexander, D.J. and Pope, G. (1972) Studies on the cytopathic effects
of Newcastle disease virus:
Cell surface changes. J.
Gen. Virol. 15, 219-225.
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27.
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Poste, G. (1972)
Mechanisms of virus-induced cell fusion. In: International
Review of Cytology (eds. J.F. Danielli and K. Jeon) Vol. 33, pp.
157-252. Academic Press, New
York.
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28.
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Poste, G. and Moss,
C. (1972) The study of surface reactions in biological systems by
ellipsometry. In: Progress in Surface Science
(ed. S.G. Davison) Vol. 2, pp. 139-232. Pergamon Press, Oxford.
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29.
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Poste, G. and Reeve,
P. (1972) Enucleation of mammalian cells by cytochalasin B. II. Formation of hybrid cells and
heterokaryons by fusion of anucleate and nucleated cells. Exp. Cell Res. 73, 287-294.
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30.
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Poste, G. (1972)
Changes in susceptibility of normal cells to agglutination by plant lectins
following modification of cell coat material. Exp. Cell Res. 73, 319-328.
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31.
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Poste, G., Waterson,
A.P., Terry, G. and Alexander, D. J. and Reeve, P. (1972) Cell fusion by
Newcastle disease virus. J.
Gen. Virol. 16, 95-97.
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32.
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Poste, G., Reeve,
P., Alexander, D.J. and Terry, G. (1972) Studies on the cytopathogenicity
of Newcastle disease virus:
Effect of lectins on virus infected cells. J. Gen. Virol. 17, 81-89.
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33.
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Poste, G., Reeve,
P., Alexander, D.J. and Terry, G. (1972) Effect of plasma membrane lipid
composition on cellular susceptibility to virus-induced cell fusion. J. Gen. Virol. 17, 133-136.
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34.
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Poste, G. (1972)
Characterization of a new canine herpes virus. Arch. Ges. Virusforsch 36, 147-157.
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35.
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Poste, G., Lecatsas,
G. and Apostolov, K. (1972) Electron microscope study of the morphogenesis
of a new canine herpesvirus in dog kidney cell. Arch. Ges. Virusforsch 39, 317-329.
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36.
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Poste, G., Hawkins,
D.F. and Thomlinson, J. (1972) Herpesvirus hominis infection of the female
genital tract. Obstetrics
and Gynecology 40, 871-890.
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37.
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Poste, G. (1972)
Electron microscope study of nuclear and nucleolar changes in cells infected
with canine distemper virus. Arch.
Ges. Virusforsch 37, 183-190.
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38.
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Alexander, DJ., Reeve, P. and Poste, G. (1973) Studies
on the cytopathic effects of Newcastle disease virus: RNA synthesis in
infected cells. J.Gen. Virol. 18, 369-373.
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39.
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Lecatsas, G. and
Poste, G. (1973) Mechanism of envelopment of herpesvirus by the nuclear
envelope. Onderstepoort J.
Vet. Res. 40, 71-72.
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40.
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Poste, G. (1973) The
synthesis of surface coat materials in normal and transformed cells. Exp. Cell Res. 77, 264-270.
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41.
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Poste, G., Greenham,
L.W., Mallucci, L., Reeve, P. and Alexander, D.J. (1973) The study of
cellular "microexudates" by ellipsometry and their relationship
to the cell coat. Exp. Cell
Res. 78, 303-313.
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42.
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Papahadjopoulos, D.,
Poste, G. and Schaeffer, B. (1973) Fusion of mammalian cells by unilamellar
lipid vesicles: Influence of
lipid surface charge, fluidity and cholesterol. Biochim. Biophys. Acta 323, 23-42.
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43.
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Alexander, D.J.,
Hewlett, G., Reeve, P. and Poste, G. (1973) Studies on the cytopathic
effects of Newcastle disease virus:
The cytopathogenicity of strain Herts 33 in five cell types. J. Gen. Virol. 21, 323-337.
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44.
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Poste, G. (1973)
Anucleate mammalian cells: Applications in cell biology and virology. In: Methods in Cell Biology (ed. D.M. Prescott) Vol.
7, pp. 211-249. Academic
Press, New York.
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45.
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Poste, G. and
Allison, A.C. (1973) Membrane fusion.
Biochim. Biophys. Acta 300, 421-465.
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46.
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Poste, G.,
Schaeffer, B., Reeve, P. and Alexander, D.J. (1974) Rescue of Simian virus
40 (SV40) from SV40-transformed cells by fusion with anucleate monkey cells
and variation in the yield of virus rescued by fusion with replicating or
nonreplicating monkey cells. Virology
50, 85-95.
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47.
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Poste, G. and Reeve,
P. (1974) Increased mobility and redistribution of concanavalin A receptors
on cells infected with Newcastle disease virus. Nature 247, 469-471.
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48.
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Papahadjopoulos, D.,
Poste, G., Schaeffer, B.E. and Vail, W.J. (1974) Membrane fusion and
molecular segregation in phospholipid vesicles. Biochim. Biophys.
Acta 352, 10-28.
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49.
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Poste, G.,
Alexander, D.J., Reeve, P. and Hewlett, G. (1974) Modification of Newcastle
disease virus release and cytopathogenicity in cells treated with plant
lectins. J. Gen. Virol.
23, 255-270.
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50.
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Papahadjopoulos, D.,
Poste, G. and Mayhew, E. (1974) Cellular uptake of cyclic AMP captured
within phospholipid vesicles and effect on cell growth behaviour. Biochim. Biophys. Acta 363,
404-418.
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51.
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Reeve, P., Hewlett,
G., Watkins, H., Alexander, D.J. and Poste, G. (1974) Virus-induced cell
fusion enhanced by phytohaemagglutinin. Nature 249, 355-356.
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52
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Papahadjopoulos, D.,
Mayhew, E., Poste, G., Smith, S. and Vail, W.J. (1974) Incorporation of
lipid vesicles by mammalian cells provides a potential method for modifying
cell behavior. Nature
252, 163-166.
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53.
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Mayhew, E., Poste,
G., Cowden, M., Tolson, N. and Maslow, D. (1974) Cellular binding of 3H-cytochalasin B. J. Cell Physiol. 84,
373-382.
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54.
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Papahadjopoulos, D.,
Poste, G. and Mayhew, E. (1975) Interaction between cells, liposomes and
micelles. Biochemical
Society Transactions 3, 606-608.
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55.
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Weiss, L., Poste,
G., MacKearnin, A. and Willett, K. (1975) Growth of mammalian cells on substrates
coated with cellular microexudates.
I. Effect on cell growth at low population densities. J. Cell Biol. 64, 135-145.
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56.
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Poste, G. (1975)
Production of macrophage migration inhibitory factor(s) (MIF) by
virus-transformed cells. Exp.
Cell Res. 92, 283-290.
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57.
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Poste, G. (1975)
Production of a serine-protease with macrophage migration inhibitory factor
activity by virus-transformed cells and human tumor cell lines. Cancer Research 35,
2558-2566.
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58.
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Poste, G.,
Papahadjopoulos, D., Jacobson, K. and Vail, W.J. (1975) Local anaesthetics
increase susceptibility of untransformed cells to agglutination by
concanavalin A. Nature
253, 552-554.
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59.
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Papahadjopoulos, D.,
Vail, W.J., Jacobson, K. and Poste, G. (1975) Cochleate lipid
cylinders: Formation by fusion
of unilamellar lipid vesicles.
Biochim. Biophys. Acta 394, 483-491.
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60.
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Papahadjopoulos, D.,
Jacobson, K., Poste, G. and Shepard, G. (1975) Effects of local anesthetics
on membrane properties. I.
Changes in the fluidity of phospholipid bilayers. Biochim. Biophys. Acta 394, 504-519.
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61.
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Poste, G.,
Papahadjopoulos, D., Jacobson, K. and Vail, W.J. (1975) Effects of local
anesthetics on membrane properties.
II. Enhancement of the susceptibility of mammalian cells to
agglutination by plant lectins.
Biochim. Biophys. Acta 394, 520-539.
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62.
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Papahadjopoulos, D.
and Poste, G. (1975) Calcium-induced phase separation and fusion in
phospholipid membranes. Biophys.
J. 15, 945-948.
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63.
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Poste, G.,
Papahadjopoulos, D. and Nicolson, G.L. (1975) Local anesthetics affect
transmembrane cytoskeletal control of mobility and distribution of cell
surface receptors. Proc.
Nat. Acad. Sci. USA 72, 4430-4434.
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64.
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Weiss, L., Subjeck,
J.R. and Poste, G. (1975) Some electrical properties of the peripheries of
murine 3T3 cells with respect to viral transformation and reversion. Int. J. Cancer 16, 914-921.
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65.
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Poste, G. (1975)
Interaction of concanavalin A with the surface of virus-infected
cells. In: Concanavalin A. (eds. T.K. Chowdhury and A.K.
Weiss) pp. 117-152. Plenum Press, New York.
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66.
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Poste, G. and
Waterson, A.P. (1975) Herpesvirus infection and cervical cancer. In: Gynaecological Malignancy. (eds. M.G. Brush and
R.W. Taylor) pp.87-108.
Balliere Tindall, London.
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67.
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Poste, G. and
Waterson, A.P. (1975) Cell fusion by Newcastle disease virus. In: Negative Strand Viruses. (eds. B.W.J. Mahy and
R.D. Barry) Vol. 2, pp. 905-922.
Academic Press, London.
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68.
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Nicolson, G.L.,
Smith, J.R. and Poste, G. (1976) Effects of local anesthetics on cell
morphology and membrane-associated cytoskeletal organization in BALB/3T3
cells. J. Cell Biol.
68, 395-402.
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69.
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Poste, G. and
Nicolson, G.L. (1976) Calcium ionophores A23187 and X537A affect cell
agglutination by lectins and capping of lymphocyte surface
immunoglobulins. Biochim.
Biophys. Acta 426, 148-155.
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70.
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Jacobson, K., Wu, J.
and Poste, G. (1976) Measurement of the translational mobility of
concanavalin A in glycerol-saline solutions and on the cell surface by
fluorescence recovery after photobleaching. Biochim. Biophys. Acta 433, 215-222.
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71.
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Poste, G. and
Papahadjopoulos, D. (1976) Lipid vesicles as carriers for introducing
materials into cultured cells:
Influence of vesicle lipid composition on mechanism(s) of vesicle
incorporation into cells. Proc.
Nat. Acad. Sci. USA 73, 1603-1607.
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72.
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Poste, G. and
Papahadjopoulos, D. (1976) Drug-containing lipid vesicles render
drug-resistant tumour cells sensitive to actinomycin D. Nature 261, 699-701.
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73.
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Jacobson, K.,
Derzko, Z., Wu, E.-S., Hou, Y. and Poste, G. (1976) Measurement of the
lateral mobility of cell surface components in single, living cells by
fluorescence recovery after photobleaching. J. Supramolec. Structure 5, 565-576.
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74.
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Papahadjopoulos, D.,
Hui, S., Vail, W.J. and Poste, G. (1976) Studies on membrane fusion. I. Interactions of pure
phospholipid membranes and the effect of myristic acid, lysolecithin,
proteins and dimethylsulfoxide.
Biochim. Biophys. Acta 448, 245-264.
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75.
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Papahadjopoulos, D.,
Vail, W.J., Pangborn, W.A. and Poste, G. (1976) Studies on membrane
fusion. II. Induction of
fusion in pure phospholipid membranes by calcium ions and other divalent
metals. Biochim. Biophys.
Acta 448, 265-283.
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76.
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Papahadjopoulos, D.,
Poste, G., Vail, W.J. and Biedler, J.L. (1976) Use of lipid vesicles as
carriers to introduce antinomycin D into resistant tumor cells. Cancer Research 36,
2988-2994.
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77.
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Weiss, L. and Poste,
G. (1976) The tumor cell periphery.
In: Scientific Foundations of Oncology. (eds. T. Symington and R.L. Carter)
pp. 25-35. Heinemann, London.
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78.
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Poste, G. and Weiss,
L. (1976) Some considerations on cell surface alterations in
malignancy. In: Fundamental Aspects of
Metastasis. (ed. L. Weiss)
pp. 25-47. Elsevier/North-Holland,
Amsterdam.
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79.
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Nicolson, G. L. and
Poste, G. (1976) Medical Progress.
The cancer cell: Dynamic aspects and modifications in cell-surface
organization. (First of Two
Parts) New England J. Med.
295, 197-203.
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80.
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Nicolson, G. L. and
Poste, G. (1976) Medical Progress.
The cancer cell:
Dynamic aspects and modifications in cell-surface organization. (Second of Two Parts) New England J. Med. 295,
253-258.
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81.
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Poste, G.,
Alexander, D. and Reeve, P. (1976) Enhancement of virus-induced cell fusion
by phytohemagglutinin.
In: Methods in Cell
Biology. (ed. D.M.
Prescott) Vol. 14, pp. 1-10.
Academic Press, New York.
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82.
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Poste, G. and
Papahadjopoulos, D. (1976) Fusion of mammalian cells by lipid vesicles. In: Methods in Cell Biology. (ed. D.M. Prescott) Vol. 14, pp.
23-32. Academic Press, New
York.
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83.
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Poste, G.,
Papahadjopoulos, D. and Vail, W.J. (1976) Lipid vesicles as carriers for
introducing biologically active materials into cells. In: Methods in Cell Biology. (ed. D.M. Prescott) Vol. 14, pp.
33-71. Academic Press, New
York.
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84.
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Poste,
G. (1976) Changes in cell surface membranes associated with malignant
transformation. In: Biological Handbooks: Cell
Biology. (eds. P.L. Altman
and D.D. Katz) Vol. 1, pp. 134-138.
Federation of American Societies for Experimental Biology, Bethesda,
Maryland
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85.
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Poste,
G. and Nicolson, G.L. (1976) Editors.
Cell Surface Reviews, Volume 1. The Cell Surface in Animal Embryogenesis and
Development.
Elsevier/North-Holland, Amsterdam. 766 pages.
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86.
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Nicolson, G. L. and Poste, G. (1976) Cell shape changes
and transmembrane receptor uncoupling induced by tertiary amine local
anesthetics. J.
Supramolecular Structure 5, 65-72.
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87.
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Papahadjopoulos, D.,
Vail, W.J., Newton, C., Nir, S., Jacobson, K., Poste, G. and Lazo, R.
(1977) Studies on membrane fusion.
III. The role of calcium-induced phase changes. Biochim. Biophys. Acta 465,
579-598.
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88.
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Poste, G. (1977) The
cell surface and metastasis.
In: Cancer Invasion
and Metastasis: Biologic Mechanisms and Therapy. (ed. S.B. Day) pp. 19-47. Raven Press, New York.
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89.
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Nicolson, G.L.,
Giotta, G., Lotan, R., Neri, A. and Poste, G. (1977) Modifications in
transformed and malignant tumor cells. In: International
Cell Biology. (eds. B.R.
Brinkley and K.R. Porter) pp. 138-148. Rockefeller University Press, New York.
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90.
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Nicolson, G.L.,
Poste, G. and Ji, J.H. (1977) The dynamics of cell membrane
organization. In: Dynamic Aspects of Cell Surface
Organization. (eds. G.
Poste and G.L. Nicolson) Cell Surface Reviews, Vol. 3, pp. 1-73. Elsevier/North-Holland, Amsterdam.
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91.
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Poste, G. and
Nicolson, G.L. (1977) Editors.
Cell Surface Reviews, Volume 2. Virus Infection and the Cell Surface. Elsevier/North-Holland,
Amsterdam. 350 pages.
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92.
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Poste, G. and
Nicolson, G.L. (1977) Editors.
Cell Surface Reviews, Volume 3. Dynamic Aspects of Cell Surface Organization. Elsevier/North-Holland,
Amsterdam. 750 pages.
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93.
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Poste, G. and
Nicolson, G.L. (1977) Editors.
Cell Surface Reviews, Volume 4. The Synthesis, Assembly and Turnover of Cell Surface Components. Elsevier/North-Holland,
Amsterdam. 883 pages.
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94.
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Fidler, I.J.,
Roblin, R.O. and Poste, G. (1978) In vitro tumoricidal activity of
macrophages against virus-transformed lines with temperature-dependent
transformed phenotypic characteristics. Cell. Immunol. 38, 131-146.
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95.
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Poste, G., Porter,
C.W. and Papahadjopoulos, D. (1978) Identification of a potential artifact
in the use of electron microscope autoradiography to localize saturated
phospholipids in cells. Biochim.
Biophys. Acta 510, 256-263.
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96.
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Nicolson, G.L. and
Poste, G. (1978) Mechanism of resistance to ricin toxin in selected mouse
lymphoma cell lines. J.
Supramolec. Structure 8, 235-245
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97.
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Poste, G. and
Papahadjopoulos, D. (1978) The influence of vesicle membrane properties on
the interaction of lipid vesicles with cultured cells. Ann. N.Y. Acad. Sci.
308, 164-184.
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98.
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Poste, G. and
Pasternak, C.A. (1978) Virus-induced cell fusion. In: Membrane
Fusion. (eds. G. Poste and
G.L. Nicolson) Cell Surface Reviews, Vol. 5, pp. 305-367. Elsevier/North-Holland, Amsterdam.
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99.
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Poste, G. and Lyon,
N. (1978) Enucleation of cultured animal cells by cytochalasin B. In: Cytochalasins -
Biochemical and Cell Biological Aspects. (ed. S. Tanenbaum) pp.
161-189.
Elsevier/North-Holland, Amsterdam.
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100.
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Poste, G., Reeve, P.
and Bachmeyer, H. (1978) Interaction of lipid vesicles containing
paramyxovirus envelope glycoproteins with cultured cells. In: Negative Strand Viruses and the Host Cell. (eds. B.W.J. Mahy and R.D. Barry)
pp. 815-823. Academic Press,
New York.
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101.
|
Poste, G. and
Nicolson, G.L. (1978) Editors.
Cell Surface Reviews, Volume 5. Membrane Fusion. Elsevier/North-Holland, Amsterdam. 862 pages.
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102.
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Poste, G., Kirsh, R.
and Fidler, I.J. (1979) Cell surface receptors for lymphokines. I. The possible role of glycolipids
as receptors for macrophage migration inhibitory factor (MIF) and
macrophage activation factor (MAF).
Cell. Immunol. 44, 71-88.
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103.
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Poste, G., Allen, H.
and Matta, K.L. (1979) Cell surface receptors for lymphokines. II. Studies on the carbohydrate
composition of the MIF receptor on macrophages using synthetic saccharides
and plant lectins. Cell.
Immunol. 44, 89-98.
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104.
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Poste, G., Kirsh,
R., Fogler, W. and Fidler, I.J. (1979) Activation of tumoricidal properties
in mouse macrophages by lymphokines encapsulated in liposomes. Cancer Research 39, 881-892.
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105.
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Poste, G. and Kirsh,
R. (1979) Rapid decay of tumoricidal activity and loss of responsiveness to
lymphokines in inflammatory macrophages. Cancer Research 39, 2582-2590.
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106.
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Poste, G. and Flood,
M.K. (1979) Cells transformed by temperature-sensitive mutants of avian
sarcoma virus cause tumors in vivo at both permissive and nonpermissive
temperatures. Cell 17,
789-800.
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107.
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Nicolson, G.L. and
Poste, G. (1979) Lectin-mediated agglutination of murine lymphoma cells:
cell surface deformability and reversibility of agglutination by
saccharides. Biochim.
Biophys. Acta 554, 520-531.
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108.
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Poste, G. (1979) The
tumoricidal properties of inflammatory tissue macro-phages and
multinucleate giant cells. Am.
J. Pathol. 96, 595-608.
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109.
|
Poste, G. (1979) The
surface properties of invasive and metastatic tumour-cell populations. British J. Cancer 39,
467-469.
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|
110.
|
Papahadjopoulos, D.,
Poste, G. and Vail, W.J. (1979) Studies on membrane fusion with natural and
model membranes. In: Methods
in Membrane Biology. (ed.
E. Korn) pp. 1-121. Plenum
Press, New York.
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111.
|
Poste, G. and
Nicolson, G.L. (1980) Arrest and metastasis of blood-borne tumor cells are
modified by fusion of plasma membrane vesicles from highly metastatic
cells. Proc. Nat. Acad.
Sci. USA 77, 399-403.
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112.
|
Poste, G. and
Fidler, I.J. (1980) The pathogenesis of cancer metastasis. Nature 283, 139-146.
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113.
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Sone, S., Poste, G.
and Fidler, I.J. (1980) Rat alveolar macrophages are susceptible to
activation by free and liposome-encapsulated lymphokines. J. Immunol. 124, 2197-2202.
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114.
|
Poste, G., Doll, J.,
Hart, I.R. and Fidler, I.J. (1980) In vitro selection of murine B16
melanoma variants with enhanced tissue-invasive properties. Cancer
Research 40, 1636-1644.
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|
115.
|
Fidler, I.J., Raz,
A., Fogler, W.E., Kirsh, R., Bugelski, P. and Poste, G. (1980) Design of
liposomes to improve delivery of macrophage augmenting agents to alveolar
macrophages. Cancer
Research 40, 4460-4466.
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116.
|
Poste, G., N.C., Macander, P., C.W.,
Reeve, P. and Bachmeyer, H. (1980) Liposome-mediated transfer of integral
membrane glycoproteins into the plasma membrane of cultured cells. Exp.
Cell Research 129, 393-408
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117.
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Poste, G. (1980)
Surface molecules and tumour-cell metastatic properties. Biochem. Soc. Trans. 8,
695-697.
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118.
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Poste, G. (1980) The
interaction of lipid vesicles (liposomes) with cultured cells and their use
as carriers for drugs and macromolecules. In: Liposomes
in Biological Systems.
(eds. G. Gregoriadis and A.C. Allison) pp. 101-151. J. Wiley, New York.
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119.
|
Poste, G. (1980) The
influence of cell surface properties on the arrest of circulating melanoma
cells. In: Tumor Cell Surfaces and
Malignancy. (eds. R.O. Hynes and C.F. Fox) pp. 737-745. Alan R. Liss, New York.
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120.
|
Poste, G., Kirsh,
R., Raz, A., Sone, S., Bucana, C., Fogler, W.E. and Fidler, I.J. (1980)
Activation of tumoricidal properties in macrophages by
liposome-encapsulated lymphokines:
In vitro studies.
In: Liposomes and
Immunobiology. (eds. B. Tom and H. Six) pp. 93-107. Elsevier/North-Holland, Amsterdam.
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121.
|
Fidler, I.J., Raz,
A., Fogler, W.E. and Poste, G. (1980) Pulmonary local-iation of
intravenously injected liposomes. In: Recent Results in Cancer
Research. (eds. G. Mathe and F.M. Muggia) Vol. 75, pp.
246-251. Springer Verlag, Berlin
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122.
|
Fidler, I.J., Hart,
I.R., Raz, A., Fogler, W.E., Kirsh, R. and Poste, G. (1980) Activation of
tumoricidal properties in macrophages by liposome-encapsulated lymphokines:
In vivo studies. In: Liposomes and Immunobiology. (eds. B. Tom and H. Six) pp.
109-118.
Elsevier/North-Holland, Amsterdam
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123.
|
Cotman, C., Poste,
G. and Nicolson, G.L. (1980) Editors.
Cell Surface Reviews, Volume 6. The Cell Surface and Neuronal Function. Elsevier/North-Holland,
Amsterdam. 546 pp.
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|
124.
|
Raz, A., Bucana, C.,
Fogler, W.E., Poste, G. and Fidler, I.J. Biochemical, morphological, and
ultrastructural studies on the uptake of liposomes by murine
macrophages. Cancer
Research 41, 487-494.
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125.
|
Fidler, I.J., Raz,
A., Fogler, W.E., Hoyer, L.C. and Poste, G. (1981) The role of plasma
membrane receptors and the kinetics of macrophage activation by lymphokines
encapsulated in liposomes. Cancer
Research 41, 495-504.
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126.
|
Hart, I.R., Fogler,
W.E., Poste, G. and Fidler, I.J. (1981) Toxicity studies of
liposome-encapsulated immunomodulators administered intravenously to dogs
and mice. Cancer Immunol.
Immunother. 10, 157-166.
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127.
|
Poste, G., Doll, J.
and Fidler, I.J. (1981) Interactions among clonal subpopulations affect the
stability of the metastatic phenotype in poly-clonal populations of B16
melanoma cells. Proc. Nat.
Acad. Sci. USA 78, 6226-6230.
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128.
|
Poste, G. and
Fidler, I.J. (1981) Activation of macrophages by lymphocyte mediators
encapsulated in liposomes.
In: Manual of
Macrophage Methodology. (eds. H.B. Herscowitz, H.T. Holden, J.A.
Bellanti and A. Ghaffar) pp. 431-438.
Marcel Dekker, New York.
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|
129.
|
Fidler, I.J. and
Poste, G. (1981) Macrophage destruction of micrometastases.
In: Manual of Macrophage
Methodology. (eds. H.B.
Herscowitz, H.T. Holden, J.A. Bellanti and A. Ghaffar) pp. 509-514. Marcel Dekker, New York
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130.
|
Poste, G. and
Fidler, I.J. (1981) Stimulation of macrophage-mediated destruction of lung
metastases by administration of immunomodulators encapsulated in
liposomes. In: Liposomes, Drugs and
Immunocompetent Cell Functions.
(eds. C. Nicolau and A. Paraf) pp. 147-161. Academic Press, New York
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131.
|
Fidler, I.J. and
Poste, G. (1981) Treatment of spontaneous murine metas-tases by the systemic
administration of liposomes containing macrophage-activating agents. In: Cancer: Achievements, Challenges and Prospects for
the 1980s. (eds J.H.
Burchemall and H.F. Oettgen) Vol. 2, pp. 77-89. Grune and Stratton, New York.
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132.
|
Fidler, I.J. and
Poste, G. (1981) Activation of tumoricidal properties in murine macrophages
by intravenous injection of muramyl dipeptide encap-sulated within
liposomes as a treatment for spontaneous metastasis. In: The Prostatic Cell: Structure and Function. (eds. G.P. Murphy, A.A. Sandberg
and J.P. Karr) Part B, pp. 257-267.
Alan R. Liss, New York.
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133.
|
Poste, G. and Flood,
M.K. (1981) Cells transformed by temperature-sensitive mutants of avian
sarcoma virus cause tumors in vivo at both permissive and nonpermissive
temperatures. In: Readings in Mammalian Cell
Culture. (ed. R. Pollack)
pp. 351-362. Cold Spring
Harbor Laboratory, New York.
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134.
|
Poste, G. and
Nicolson, G.L. (1981) Editors.
Cell Surface Reviews, Volume 7. Cytoskeletal Elements and Plasma Membrane
Organization.
Elsevier/North-Holland, Amsterdam. 349 pp.
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135.
|
Fidler, I.J. and
Poste, G. (1982) The biologic diversity of cancer metastases. Hospital Practice 17, 57-64.
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136.
|
Fidler, I.J.,
Barnes, Z., Fogler, W.E., Kirsh, R., Bugelski, P. and Poste, G. (1982)
Involvement of macrophages in the eradication of established metastases
following intravenous injection of liposomes containing macrophage
activators. Cancer Research
42, 496-501.
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|
137.
|
Poste, G., Bucana,
C., Raz, A., Bugelski, P., Kirsh, R. and Fidler, I.J. (1982) Analysis of
the fate of systemically administered liposomes and implications for their
use in drug delivery. Cancer
Research 42, 1412-1422.
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|
138.
|
Poste, G., Doll, J.,
Brown, A.E., Tzeng, J. and Zeidman, I. (1982) Comparison of the metastatic
properties of B16 melanoma clones isolated from cultured cell lines,
subcutaneous tumors, and individual lung metastases. Cancer Research 42,
2770-2778.
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139.
|
Poste, G. and Greig,
R. (1982) On the genesis and regulation of cellular heterogeneity in
malignant tumors. Invasion
and Metastasis 2, 137-176
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140.
|
Fidler, I.J. and
Poste, G. (1982) Macrophage-mediated destruction of malignant tumor cells
and new strategies for the therapy of metastatic disease. Springer Semin. Immunopathol.
5, 161-174.
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|
141.
|
Poste, G., Tzeng,
J., Doll, J., Greig, R., Rieman, D. and Zeidman, I. (1982) Evolution of
tumor cell heterogeneity during progressive growth of individual lung
metastases. Proc. Nat.
Acad. Sci. USA 79, 6574-6578.
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|
142.
|
Badger, A.,
Griswold, D.E., DiMartino, M.J. and Poste, G. (1982) Inhibition of antibody
synthesis by histamine in concanavalin A-treated mice: The possible role of
glucocorticosteroids J.
Immunol. 129, 1017-1022.
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|
143.
|
Sitrin, R.D.,
Antell, L.A., Griswold, D.E., Bender, P.E., Greig, R.G. and Poste, G.
(1982) A high performance liquid chromatography assay for the rapid analysis
of the subunit content of concanavalin A. Biochim. Biophys. Acta 717 (1) 175-178.
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144.
|
Poste, G. (1982)
Cellular heterogeneity in malignant neoplasms and the therapy of
metastases. Ann. N.Y. Acad.
Sci. 391, 34-48.
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145.
|
Poste, G. and
Fidler, I.J. (1982) Active non-specific immunotherapy of lung metastases by
macrophages activating agents encapsulated in liposomes. In: Optimization of Drug
Delivery, Alfred Benzon Symposium 17. (eds. H. Bundgaard, A. Bagger Hansen and H. Kofod) pp.
418-431. Munksgaard,
Copenhagen.
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146.
|
Poste, G. and
Fidler, I.J. (1982) Therapeutic amplification of macrophage-mediated
destruction of tumor cells: An approach to cancer therapy that addresses
the problem of tumor cell heterogeneity. In: Design
of Models for Testing Cancer Therapeutic Agents. (eds. I.J. Fidler and R.J. White)
pp. 225-238. Van Nostrand, New
York.
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147.
|
Poste, G. (1982)
Methods and models for studying tumor invasion. In: Tumor
Invasion and Metastasis. (eds.
L.A. Liotta and I.R. Hart) pp. 147-171. Martinus Nijhoff, Amsterdam.
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148.
|
Brown, A.E., Badger,
A.M. and Poste, G. (1982) The effect of cimetidine on immune cell function
and host response to tumors.
In: Current Concepts
in Human Immunology and Cancer Immunomodulation. (ed. B. Serrou) pp. 513-519. Elsevier, Amsterdam.
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149.
|
Poste, G. (1982)
Liposomes as a carrier system for improved delivery of biologically-active
materials to cells in vitro and in vivo. In: Liposome
Methodology. (eds. L.D.
Leserman and J. Barbet) pp. 65-77.
Inserm, Paris
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150.
|
Poste, G. (1982)
Variation in the metastatic properties of cells from malignant tumors and
the control of the metastatic phenotype. In: Tumour
Progression and Markers.
(ed. M. Price) pp. 197-210.
Kugler Publications, Amsterdam.
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151.
|
Nicolson, G.L. and
Poste, G. (1982) Tumor cell diversity and host responses in cancer
metastasis. I. Properties of
metastatic cells. In: Current Problems in Cancer. (ed. R.C. Hickey) pp. 1-83. Yearbook Medical Publishers,
Chicago.
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152.
|
Fidler, I.J. and
Poste, G. (1982) Macrophages and Cancer Metastasis. In: Macrophages and Natural Killer Cells. Advances in Experimental Medicine
and Biology, Vol. 155. (eds. S.J. Normann and E. Sorkin) pp. 65-75. Plenum Press, New York.
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153.
|
Poste, G. (1982) Experimental
systems for analysis of the malignant pheno-type. In: Cancer and
Metastasis Reviews. (ed. I.J. Fidler) Vol. 1, pp. 141-199.
Martinus Nijhoff, Amsterdam.
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154.
|
Fidler, I.J. and
Poste, G. (1982) The heterogeneity of metastatic properties in malignant
tumor cells and regulation of the metastatic phenotype. In: Tumor Cell Heterogeneity: Origins and Implications. (eds. A. Owens, Coffey, D. S., and S. Balin) pp.
127-145. Academic Press, New
York.
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155.
|
Poste, G. and Kirsh,
R. (1982) Liposome-encapsulated macrophage activation agents and active
non-specific immunotherapy of neoplastic disease. In: Cell
Function and Differentiation, Part A. (ed. A. Evangelopoulos) pp. 309-319. Alan R. Liss, New York.
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156.
|
Poste, G., Bucana,
C. and Fidler, I.J. (1982) Stimulation of host response against metastatic
tumors by liposome-encapsulated immunomodulators. In: Targeting
of Drugs. (eds. G.
Gregoriadis, J. Senior and A. Trouet) NATO Advanced Studies Institute
Series, Vol. A47, pp. 261-284.
Plenum Press, New York.
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157.
|
Poste, G. and
Nicolson, G.L. (1982) Editors.
Cell Surface Reviews, Volume 8. Membrane Reconstitution. Elsevier/North-Holland,
Amsterdam. 360 pages.
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158.
|
Poste, G. (1983)
Tumor cell heterogeneity and the metastatic process. In: Understanding Breast Cancer: Clinical and Laboratory
Concepts. (eds. M.A. Rich,
J.C. Hager and P. Furmanski) pp. 119-143. Marcel Dekker, Inc., New York.
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159.
|
Greig, R. G.,
Caltabiano, L., Reid, Jr., R., Feild, J. and Poste, G. (1983) Heterogeneity of protein
phosphorylation in metastatic variants of B16 melanoma. Cancer Research 43,
6057-6065.
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|
160.
|
Bugelski, P.J.,
Kirsh, R.L. and Poste, G. (1983) New histochemical method for measuring
intratumoral macrophages and macrophage recruitment into experimental
metastases. Cancer Research
43, 5493-5501.
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161.
|
Badger, A., Young,
J. and Poste, G. (1983) Inhibition of phytohaemagglutinin-induced
proliferation of human peripheral blood lymphocytes by histamine and histamine
H1 and H2 agonists. Clin.
Exp. Immunol. 51, 178-184.
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|
162.
|
Badger, A., Brown,
A.E. and Poste, G. (1983) The effect of cimetidine on antibody synthesis in
vitro and in vivo. Immunology
48, 151-155.
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163.
|
Griswold, D.E.,
Badger, A.M., Bender, P.E., Sitrin, R.D., Antell, L., Greig, R.G. and
Poste, G. (1983) Differential effects of intact subunits and nicked
fragments of concanavalin A on immune functions in vitro and in vivo. J. Immunol. 131, 1626-1628.
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164.
|
Hanna, N.,
DiMartino, M., Griswold, D.E. and Poste, G. (1983) Immunology of
auranofin. Current Clinical
Practice 7, 60-70.
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165.
|
Poste,
G. and Kirsh, R. (1983) Site-specific (targeted) drug delivery in cancer
therapy. Biotechnology
1, 869-878.
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166.
|
Poste, G. and
Nicolson, G.L. (1983) Experimental systems for analysis of the surface
properties of metastatic tumor cells.
In: Biomembranes. (ed. A. Nowotny) Vol. 11, pp.
341-364. Plenum Press, New
York.
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167.
|
Poste, G. (1983)
Liposome targeting in vivo: problems and opportunities. In: Liposomes in Vivo. (eds. C. Nicolau and G. Poste). Biol. Cell. 47, pp. 19-38.
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168.
|
Nicolson, G.L. and
Poste, G. (1983) Tumor cell diversity and host responses in cancer
metastasis. II. Host immune
responses and therapy of metastases In: Current Problems in Cancer. (ed. R.C. Hickey) Vol. 7, pp.
1-42. Yearbook Medical
Publishers, Chicago.
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169.
|
Kirsh, R. and Poste,
G. (1983) Stimulation of host resistance to metastatic tumors by macrophage
activating agents encapsulated in liposomes. In: Host
Defenses to Intracellular Pathogens. (ed. T.K. Eisenstein) Adv. Exp. Biol. Med. Vol.
162, pp. 69-75. Raven Press,
New York.
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170.
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Poste,
G. (1983) Whatever happened to the industry I was told to distrust. Immunology Today 4, 133-136.
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171.
|
Nicolson, G.L. and
Poste, G. (1983) Tumor implantation and invasion at metastatic sites. Int. Rev. Exp. Pathol. 25,
77-181.
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172.
|
Poste, G. and Greig,
R. (1983) The experimental and clinical implications of cellular
heterogeneity in malignant tumors.
J. Cancer Res. Clin. Oncol. 106, 159-170.
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173.
|
Poste, G., Kirsh, R.
and Koestler, T. (1984) The challenge of liposome targeting in vivo. In: Liposome Technology (ed. G. Gregoriadis) Vol. 3, pp.1-28. CRC Press, Boca Raton, Florida.
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174.
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Kirsh, R. and Poste,
G. (1984) Liposome encapsulation of biological response modifiers: Activation of tumoricidal macrophages. In: Liposome Technology (ed. G. Gregoriadis) Vol. 2, pp. 33-53. CRC Press, Boca Raton, Florida.
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175.
|
Sheppard, J.R.,
Koestler, T., Corwin, S., Buscarino, C., Doll, J., Lester, B., Greig, R.
and Poste, G. (1984) Experimental metastasis correlates with cyclic AMP
accumulation in B16 melanoma clones.
Nature 308, 544-547.
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176.
|
Griswold, D.E.,
Alessi, S., Badger, A.M., Poste, G. and Hanna, N. (1984) Inhibition of T
suppressor cell expression by histamine type 2 (H2) receptor antagonists. J. Immunol. 132, 3054-3057.
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177.
|
Kirsh, R. and Poste,
G. (1984) Macrophage activation in vivo: New approaches to the therapy of metastatic tumors. EOS J. Immunol. Immunopharmacol.
IV, 32-35.
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178.
|
Poste, G., Tzeng,
J., Koestler, T., Corwin, S., and Greig, R. (1984) Interactions between tumor cell
subpopulations in malignant tumors.
In: Cancer Invasion
and Metastasis: Biological and
Therapeutic Aspects. (eds.
G. Nicolson and L. Milas) pp. 223-244. Raven Press, New York.
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179.
|
Poste, G. and
Nicolson, G.L. (1984) In vitro systems for studying the interaction of
metastatic tumor cells with endothelial cells and subendothelial basement
membranes. In: Biology of Endothelial Cells. (ed. E. A. Jaffe) pp. 438-448. Martinus Nijhoff, Boston.
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180.
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Poste, G. (1984)
Liposomes: fascination, frustration, feasibility and fantasy. In: Liposome Letters. (ed. A.D. Bangham) pp. 375-386. Academic Press, London.
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181.
|
Poste, G. and
Crooke, S.T. (1984) Editors.
Dopamine Receptor Agonists.
New Horizons in Therapeutics. Vol. 1. Plenum Press, New York.
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182.
|
Badger, A.M., Young,
J. and Poste, G. (1984) Reversal of histamine-mediated immunosuppression by
structurally diverse histamine type II (H2)
receptor antagonists. Int.
J. Immunopharmacol. 6, 467-473.
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183.
|
Wright, B., Greig,
R. and Poste, G. (1984) Inhibition of macrophage activation and tumor cell
cytolysis by cyclosporin A. Biochem.
Biophys. Res. Commun. 123, 710-715.
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184.
|
Kirsh, R. and Poste,
G. (1984) Liposome targeting to macrophages: Opportunities for treatment of infectious diseases. In: Infections of the
Compromised Host. (eds. P.
Actor, A. Grangelista, and J. Poupard) pp. 317-356. Plenum Press, New York.
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185.
|
Poste, G. (1984)
Tumor Cell Heterogeneity.
National Cancer Institute, Cancer Information Dissemination Center. Oncology Overview Series,
U.S. Government Printing Office.
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186.
|
Poste, G., Kirsh, R.
and Bugelski, P. (1984) Liposomes as a drug delivery system in cancer
therapy. In: Novel Approaches to Cancer
Chemotherapy. (ed. P.
Sunkara) pp. 165-230. Academic
Press, New York.
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187.
|
Poste, G. (1984)
Hype, Hope and Honesty:
Reporting of Cancer Discoveries by the Media. Biotechnology 2, 1096.
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188.
|
Kirsh, R. and Poste,
G. (1984) Liposomes and targeted drug delivery to macrophages: A potential system for improved
therapy of microbial infections.
Clin. Immunol. Newsletter 5, 168-171.
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189.
|
Poste, G. (1984) New
insights into receptor regulation.
J. Applied Physiol. 57, 1297-1305.
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190.
|
Koestler, T.P.,
Rieman, D., Muirhead, K., Greig, R.G. and Poste, G. (1984) Identification
and characterization of a monoclonal antibody to an antigen expressed on
activated macrophages
(lymphokine/hybridoma/cell surface antigens/immunofluorescence/macrophage-mediated
cytotoxicity. Proc. Nat. cad. Sci. USA. 81, 4505-4509.
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191.
|
Koestler, T.P.,
Kirsh, R., Kline, T., Rieman, D., Greig, R. and Poste, G. (1984) Production
of C3 as a marker of lymphokine-mediated macrophage activation. Cell. Immunol. 87, 1-14.
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192.
|
Poste, G., (1984)
The mystery of metastasis:
What we know, so far. Your
Patient and Cancer April, 59-61.
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193.
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Poste, G. (1985)
Tumor cell heterogeneity and the pathogenesis of cancer metastasis. In: Basic Mechanisms and Clinical Treatment of Tumor Metastasis.
(eds. Torisu, M and Yoshida, T.)
pp. 79-100. Academic
Press, New York.
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194.
|
Griswold, Don E.,
Lee, J. C., Poste, G. and Hanna, N. (1985) Modulation of
macrophage-lymphocyte interactions by the antiarthritic gold compound,
auranofin. J. Rheumatol. 12, 490-497.
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195.
|
Muirhead, K.A.,
Horan, P.K. and Poste, G. (1985) Flow Cytometry: Present and future. Biotechnology 3, 337-356.
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196.
|
Greig, R.G., Lester,
B., Sorensen, P., Buscarino, C. and Poste, G. (1985) Hormonal regulation of
B16 melanoma metastasis.
In: Treatment of
Metastasis: Problems and Prospects. (eds. K. Hellmann and S.A. Eccles.) pp. 121-124. Taylor
and Francis, London.
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197.
|
Poste, G. (1985)
Drug Targeting in Cancer Therapy.
In: Receptor-Mediated
Targeting of Drugs. (eds.
G. Gregoriadis, J. Senior, G. Poste and A. Trouet) pp. 427-474. Plenum Press, New York.
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198.
|
Ravetch, J.V.,
Young, J. and Poste, G. (1985) Molecular Genetic Strategies for the
Development of Anti-Malarial Vaccines. Biotechnology 3, 729-740.
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199.
|
Bugelski, P.J.,
Kirsh, R., Corwin, S., Sowinski, J. and Poste, G. (1985) Changes in the macrophage
content of lung metastases at different stages in tumor growth. Am. J. Pathol. 118, 419-424.
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200.
|
Ferguson, B.
Pritchard, L. Feild, J., Reiman, D., Greig, R., Poste, G. and Rosenberg, M.
(1985) Isolation analysis of an Abelson murine leukemia virus-encoded
tyrosine-specific kinase produced in E. coli. J. Biol. Chem. 260, 3652-3657.
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201.
|
Greig, R.G.,
Koestler, T.P., Trainer, D.L., Corwin, S., Miles, L., Kline, T., Sweet, R.,
Yokoyama, S. and Poste, G. (1985) Tumorigenic and metastatic properties of
"normal" and ras-transfected NIH/3T3 cells. Proc. Nat. Acad. Sci., USA 82, 3698-3701.
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202.
|
Fidler, I.J. and
Poste, G. (1985) The cellular heterogeneity of malignant neoplasms: Implications for adjuvant
chemotherapy. Seminars in
Oncology, 12, 207-221.
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203.
|
Trainer, D., Kline,
T., Mallon, F., Greig, R. and Poste, G. (1985) Effect of 5-azacytidine on
DNA methylation and the malignant properties of B16 melanoma cells. Cancer Research 45, 6124-6130.
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204.
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Poste, G. (1985)
Current concepts of cancer metastasis. Transactions and Studies of the
College of Physicians of Philadelphia series 5, 7, 239-252.
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205.
|
Wright, B., Zeidman,
I., Greig, R. and Poste, G. (1985) Inhibition of macrophage activation by
calcium channel blockers and calmodulin antagonists. Cellular Immunology 95, 46-53.
|
|
206.
|
Koestler, T.,
Badger, A., Rieman, D., Greig, R. and Poste, G. (1985) Induction by
immunomodulatory agents of a macrophage antigen recognized by monoclonal
antibody 158.2 and correlation with macrophage function. Cellular Immunology 96, 113-125.
|
|
207.
|
Greig, R.G.,
Caltabiano, L., Feild, J., Reid, Jr., R. and Poste, G. (1985) Alterations
in the phosphoprotein composition of tumor cell clones induced by cell
culture techniques used routinely in assessing metastatic behavior in
vivo. Int. J. Cancer 35, 367-375.
|
|
208.
|
Muirhead, K.,
Bender, P., Hanna, N. and Poste, G. (1985) Binding of histamine and
histamine analogs to lymphocyte subsets analyzed by flow cytometry. J. Immunol. 135, 4120-4128.
|
|
209.
|
Griswold, D.E.,
Antell, L., Bender, P.E., Hanna, N. and Poste, G. (1985) Induction of
suppressor cells, interleukin 2 production and mitogenesis with monomeric
concanavalin A: different actions of tetrameric and monomeric concanavalin
A. Mol. Immunol. 22,
1311-1316.
|
|
210.
|
Poste, G. (1985) The
pharmaceutical industry and health care in the third world. Biotechnology 3, 704-706.
|
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211.
|
Kirsh, R. and Poste,
G. (1985) Liposome mediated delivery of biological response modifiers (BRM)
to macrophages in vivo: A new
strategy for therapy of neoplastic disease. Colloids and Surfaces 14, 339-348
|
|
212.
|
Poste, G. and
Crooke, S.T. (1985) Editors.
Mechanisms of Receptor Regulation. New Horizons in Therapeutics, Vol. 2. Plenum Press, New York.
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213.
|
Poste, G. and Greig,
R. (1986) Experimental Models for Studying the Pathogenesis and Therapy of
Metastatic Disease. In: Mechanisms of Cancer Metastasis: Potential therapeutic implications. (ed. K. V. Honn) pp. 41-68 Martinus Nijhoff, Boston.
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214.
|
Poste, G. (1986)
Pathogenesis of metastatic disease:
Implications for current therapy and for the development of new
therapeutic strategies. Cancer
Treatment Reports. 70, 183-199.
|
|
215.
|
Lee, J., Rebar, L.,
Young, P., Ruscetti, F., Hanna, N. and Poste, G. (1986) Identification and
characterization of a human T cell line-derived lymphokine with MAF-like
activity distinct from gamma interferon. J. Immunol. 136, 1322-1328.
|
|
216.
|
Nicolson, G.L.,
Fidler, I.J. and Poste, G. (1986) The effects of tertiary amine local
anesthetics on the blood-borne implantation and cell surface properties of
metastatic mouse melanoma cells.
J. Nat. Cancer Inst.
76, 511-519.
|
|
217.
|
Sheppard, J. R.,
Lester, B., Doll, J., Buscarino, C., Gonzales, E., Corwin, S., Greig, R.
and Poste G. (1986) Biochemical regulation of adenylate cyclase in murine
melanoma clones with different metastatic properties. Int. J. Cancer 37, 713-722.
|
|
218.
|
Poste, G. and
Crooke, S.T. (1986) Editors.
New insights into cell and membrane transport processes. New Horizons in Therapeutics.
Vol. 3. Plenum Press, New York.
|
|
219.
|
Kirsh, R. and Poste,
G. (1986) Macrophage-mediated tumor cell destruction: opportunities for treatment of
metastatic disease. In: Receptors in Tumor Biology. (ed. C. M. Chadwick) Marcel Dekker,
New York.
|
|
220.
|
Poste, G. (1986).
Cell surface alterations and the metastatic behavior of tumor cells. In: Interaction of Cells with Natural and Foreign
Surfaces. (ed. N. Crawford) Plenum Press, New York.
|
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221.
|
Caltabiano, M. M.,
Koestler, T. P., Poste, G. and Greig, R. (1986) Induction of mammalian
stress proteins by triethylphosphine gold compound used in the therapy of
rheumatoid arthritis. Biochem.
Biophys. Res. Comm. 138, 1074-1080.
|
|
222.
|
Caltabiano, M.,
Koestler, T., Poste, G. and Greig, R. (1986) Induction of 32- and 34-kDa
stess proteins by sodium arsenite, heavy metals, and thiol-reactive agents.
J. Biol. Chem. 261, 13381-13386.
|
|
223.
|
Van Alstine, J.M.,
Sorensen, P., Webber, T.J., Greig, R., Poste, G. and Brooks, D.E. (1986)
Heterogeneity in the surface properties of B16 melanoma cells from sublines
with differing metastatic potential detected via two polymer aqueous phase
partition. Experimental
Cell Research 164, 366-378.
|
|
224.
|
Poste, G., and
Greig, R. (1986) The Cell
Surface and Cancer Metastasis.
Developmental Biology Volume 3, 15-31 (ed. M. S. Steinberg) Plenum Publishing
Corp.
|
|
225.
|
Lester, B. R.,
Greig, R. G., Buscarino, C. Sheppard, J. R., Corwin, S. P. and Poste,
G. (1986) cAMP metabolism in
B16 Melanoma clones during the formation of experimental and spontaneous
metastases. Int. J. Cancer
38, 405-411.
|
|
226.
|
Horan, P.K., Slezak,
D. and Poste, G. (1986) Improved flow cytometric analysis of leukocyte cell
subsets: Simultaneous
identification of five cell subsets using two color immunofluorescence. Proc. Nat. Acad. Sci. USA,
82, 8361-8365.
|
|
227.
|
Kirsh, R. and Poste,
G. (1986) Liposome mediated
drug delivery to mononuclear phagocytes in vivo: Applications in antimicrobial therapy. In: Medical Applications of Liposomes. (ed. K. Yagi) pp. 99-104 Karger, Basel
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228.
|
Gregoriadis, G.,
Senior, J., and Poste, G. (1986) Editors. Targeting of drugs with synthetic systems. NATO ASI
Series. Plenum Press, New York, Vol. 113.
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229.
|
Kirsh, R., and
Poste, G. (1986) Liposome targeting to macrophages: opportunities for treatment of
infectious diseases. In: Infections
in the Immunocompromised Host-Laboratory Diagnosis and Treatment. Eds. P. Actor, A. Evangelista, J.
Poupard and E. Hinks, Plenum Press, New York. pp 171-184.
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230.
|
Greig, Russell G.,
and Poste, G. (1986) Biological Membranes and Malignancy: An Overview of Pharmacological
Opportunities. In: Annals of
the New York Academy of Sciencies, Vol. 488.
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231.
|
Poste, G., Greig,
R. (1986) The Cell-Surface and
Cancer Metastasis. American
Zoologist, 26(3), 567.
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|
232.
|
Caltabiano, M.M.,
Koestler, T.P., Poste, G., Greig, R.G. (1986)
Compound used in the therapy of rheumatoid-arthritis. Biochemical and Biophysical
Research Communications, 138(3) 1074-1080.
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233.
|
Wright, B., Zeidman,
I., Greig, R., Poste, G.
(1986) Calcium fluxes
and calmodulin inhibitors in macrophage activation. Cellular Immunology, 100(2),
586-587.
|
|
234.
|
DiMartino, M.J.,
Griswold, D.E., Berkowitz, B.A., Poste, G., and Hanna, N. (1987)
Pharmacologic characterization of the antiinflammatory properties of a new
dual inhibitor of lipoxygenase and cyclooxygenase. Agents and Actions
Vol. 20, 113-123.
|
|
235.
|
Lester, B.R.,
Stadel, J.M., Buscarino, C., Sheppard, J., Greig, R.G., and Poste, G.
(1987) Reconstitution of the Gs
protein from B16 melanoma clones of high and low experimental metastatic
potential into S49 CYCmembranes.
Biochemical and Biophysical Research Communications 147,
443-451.
|
|
236.
|
Rees, R., Dalton,
B., Young, J., Hanna, N., and Poste, G. (1987) Augmentation of human
natural killer cell activity by influenza virus antigens produced in E.
Coli. J. Biol. Res. Mod.,
6, 9-87.
|
|
237.
|
Dunnington, D.J.,
Buscarino, C., Gennaro, D., Greig, R., and Poste, G. (1987)
Characterization of an animal model of metastatic colon carcinoma. Int. J. Cancer 39, 248-254.
|
|
238.
|
Bugelski, P.J.,
Kirsh, R., Buscarino, C., Corwin, S.P. and Poste, G. (1987) Recruitment of
exogenous macrophages into metastases at different stages of tumor
growth. Cancer Immunol.
Immunotherap. 24, 93-98.
|
|
239.
|
Bugelski, P.J.,
Corwin, S.P., North, S.M., Kirsh, R.L., Nicolson, G.L. and Poste, G. (1987)
Macrophage content of spontaneous metastases at different stages of
growth. Cancer Research
47, 4141-4145.
|
|
240.
|
Niewiarowska, A.,
Caltabiano, M.M., Bailey, D.S., Poste, G., and Greig, R.G. (1987)
Alterations in lipid-linked oligosaccharide metabolism in human melanoma
cells concomitant with induction of stress proteins. J. Biol. Chem. 262, 14815-14820.
|
|
241.
|
Koestler, T.,
Johnson, W., Rieman, D., Dalton, B., Greig, R., and Poste, G. (1987)
Differential expression of murine macrophage-mediated tumor cytotoxicity
induced by interferons. Cancer
Research 47, 2804-2808.
|
|
242.
|
Poste, G. (1987)
Industrial biotechnology in Europe-Issues for public policy. A Book Review The Scientist 1, 23.
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|
243.
|
Poste, G. and Crooke,
S.T. (1987) Editors. New Frontiers in the Study of Gene
Functions. New Horizons in
Therapeutics, Plenum Press, New York.
|
|
244.
|
Kirsh, R., Poste, G.
(1987) Liposome-Mediated
Macrophage Activities. Methods
in Enzymology 149, 147-157.
|
|
245.
|
Griswold, D.G.,
Webb, E.F., Godfrey, R., DiMartino, M.J., Sarau, H., Poste, G. and Hanna,
N. (1987) SK&F 86002: A
novel anti-inflammatory agent producing inhibition of lipoxygenase- and
cyclooxygenase-mediated arachidonic acid metabolism. Biochem. Pharmacol. 36,
3463-3470.
|
|
246.
|
Bailey, D.S., Kline,
T., Clark, R.K., Hoffstein, S., Poste, G., Greig, R. (1987) Glycoprotein synthesis by Human Colon Carcinoma Cells In
Vitro and As Xenografts in Nude Mice.
Biochem. Soc. Trans., 15(3), 385.
|
|
247.
|
Clark, R.K., Bailey,
D.S., Bryant, S.L., Trainer, D.L., Poste, G., Greig, R. (1987) Differentiation and carbohydrate expression in
colon-carcinoma. Proceedings
of the American Association of Cancer Research., March, Vol. 28, 39.
|
|
248.
|
Trainer, D.L.,
Clark, R., Feild, J., Chaikin, M., Kline, T., Watt, R., Poste, G., Greig,
R. (1987) Oncogene expression in primary and
metastatic human-colon carcinoma.
Gastroenterology, 92(5) 1673.
|
|
249.
|
Greig, R.G, Anzano,
M., Tainer, D., Poste, G.
(1987)
Growth-regulation in colon-carcinoma. Journal of Cellular Biochemistry. S11D, p. 85.
|
|
250.
|
Bailey, D.S., Nambi,
P., Bryant, S.L., Clark, R.K,. Trainer, D., Poste, G., Greig, R (1987) Signal transduction and differentiation of colon
carcinoma cells. J. Cell
Biol., Vol. 105.
|
|
251.
|
Trainer, D.L.,
Kline, T., McCabe, F.L., Faucette, L.F., Feild, J., Chaikin, M., Anzano,
M., Rieman, D., Hoffstein, S., Li, D., Gennaro, D., Buscarino, C., Lynch,
M., Poste, G., and Greig, R. (1988) Biological characterization and
oncogene expression in human colorectal carcinoma cell lines. Int. J. Cancer 41,
287-296.
|
|
252.
|
Poste, G. and
Crooke, S.T. (1988)
Editors. Cellular and
molecular aspects of inflammation.
New Horizons in Therapeutics Volume 5, Plenum Press, New York.
|
|
253.
|
Trainer, D., Kline,
T., Hensler, G., Greig, R., and Poste, G. (1988) Clonal analysis of the
malignant properties of B16 melanoma cells treated with the DNA
hypomethylating agent 5-azacytidine.
Clin. Expl. Metastasis 6, 185-200.
|
|
254.
|
Young, J.F., and
Poste, G. (1988) The prospects
for a human malaria vaccine. Trends
in Biotechnology 6, 63-68.
|
|
255.
|
Kirsh, R., Goldstein,
R., Tarloff, J., Parris, D., Hook, J., Hanna, N., Bugelski, P., and Poste,
G. (1988) An emulsion formulation of amphotericin B improves the
therapeutic index when treating systemic murine candidiasis. The Journal
of Infectious Diseases, 158, 5, 1065-1070.
|
|
256.
|
Caltabiano, M.M.,
Poste, G., and Greig, R.G. (1988) Induction of the 32-kDa human stress
protein by auranofin and related triethylphosphine gold analogs. Biochem. Pharmacol. 37, 21,
4089-4093.
|
|
257.
|
Kruse, C.H., Holden,
K.A., Offen, P.H., Pritchard, M.L., Feild, J.A., Rieman, D., Bender, P.E.,
Greig, R.G. and Poste, G. (1988)
Synthesis and evaluation of multisubstrate inhibitors of an
oncogene-encoded tyrosine-specific protein kinase. J. Medicinal Chemistry. 31,
1762-1772
|
|
258.
|
Caltabiano, M.M.,
Poste, G., Greig, R.G.
(1988) Isolation and
immunological characterization of the mammalian 32-/34-kDa stress protein. Experimental Cell Research,
178, 31-40.
|
|
259.
|
Poste, G., Greig,
R. (1988) New-wave cancer therapy: Disease-specific strategies. The Scientist, 2(19), 1-14.
|
|
260.
|
Gregoriadis, G.,
Poste, G. (1988) Editors.
Targeting of Drugs:
Anatomical and Physiological Considerations. (1988) NATO ASI Series. Series A: Life Sciences, Vol. 155.
|
|
261.
|
Fidler, I., Poste,
G., Murine Melanoma Metastasis.
(1988) ISI Atlas of
Science: Immunology, pp. 133-137.
|
|
262.
|
Poste, G. (1989)
Biotechnology: A new horizon
for pharmacy. U.S.Pharmacist
14, 76-83.
|
|
263.
|
Pritchard, M.L.,
Rieman, D., Feild, J., Kruse, C., Rosenberg, M., Poste, G., Greig, R.G.,,
Ferguson, B.Q. (1989) A truncated v-abl-derived
tyrosine-specific tyrosine kinase expressed in escherichia-coli. Biochem J., 257(2), 321-329.
|
|
264.
|
Bugelski, P.J.,
Gennaro, D.E., Poste, G., Hoffstein, S.T. (1989) A
new cytochemical method for ultrastructural detection of liposomes in
tissues in vivo. Journal of
Histochemistry and Cytochemistry, 37(6) 843-851.
|
|
265.
|
Moyer, M.P., and
Poste, G. (1989) Editors. Colon Cancer Cells. Academic Press, New York.
|
|
266.
|
Gregoriadis, G.,
Allison, A.C., Poste, G.
(1989) Editors.
Immunological Adjuvants and Vaccines. NATO ASI Series. Series A: Life Sciences, Vol. 179.
|
|
267.
|
Badger, A.M.,
Griswold, D.E., Poste, G., Hanna, N. (1990) Histamine modulation of murine suppressor cell function.
Histamine & H2 Antagonists
in Inflammation and Immunodeficiency,
pp. 3-21.
|
|
268.
|
Greig, R., and
Poste, G. (1990) Glycoconjugates as drugs. Glycobiology, pp. 173-193.
|
|
269.
|
Hook, J., and Poste,
G. (1990) Editors. Protein
Design and the Development of New Therapeutics and Vaccines. Plenum Press, New York.
|
|
270.
|
Gregoriadis, G.,
Allison, A.C., Poste, G. (1989)
Editors. Targeting of
drugs 2: optimization strategies.
NATO ASI Series.
Series A: Life Sciences Vol.. 199. Plenum Press, New York.
|
|
271.
|
Poste, G., The
importance of the national climate as a stimulus to research in the
USA. Reprinted from Creating
the Right Environment for Drug Discovery, Edited by Stuart R. Walker,
pp. 105-121. The Ciba
Foundation, London. Quay
Publishing.
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272.
|
Ruffolo, Jr., R.R.,
Brooks, D., Huffman, W., Poste, G., (1991) From vasopressin antagonist to agonist: a saga of surprise! Drug News & Perspectives,
4(4), 217-222.
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273.
|
Hanna, N., Poste, G.
(1991). Inflammation. Encyclopedia of Human Biology, Vol. 4, pp.
469-477. Academic Press, New
York.
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274.
|
Harris, T., Poste,
G. (1991). Pharmaceutical
applications. Current
Opinion in Biotechnology, Vol. 2, No. 2, pp. 211-214. (ed. J. Davies) Current Biology Ltd., London.
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275.
|
Gregoriadis, G.,
Allison, A., and Poste, G. (1990) Editors. Vaccines: recent trends and progress. NATO ASI Series. Series A: Life Sciences,
Vol. 215. Plenum Press, New
York.
|
|
276.
|
Brawner, M.,
Fornwald, J., Rosenberg, M., Poste, G. and Westpheling, J. (1990)
Heterologous gene expression in streptomyces. Genetics of Industrial
Microorganisms, pp. 85-93.
Heslot, H., Davies, J., Florent, J., Bobichon, L., Durand, G.,
Penasse, L., (1990) Editors.
Societe Francaise de Microbiologie, Strasbourg.
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277.
|
Brawner, M., Fornwald,
J., Rosenberg, M., Poste, G. and Westpheling, J. (1991) Streptomyces:
a host for heterologous gene expression. Current Opinion in Biotechnology, Vol. 2, pp.
674-81. Current Biology Ltd.,
London.
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278.
|
Gregoriadis, G.,
Florence, A.T., Poste, G. (1991) Editors. Targeting of drugs 3: the challenges of peptides and proteins. NATO ASI Series. Series A: Life Sciences. Vol 238. Plenum Press, New York.
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|
279.
|
Ruffolo, Jr., R.R.,
Boyle, D.A., Brooks, D.P., Feuerstein, G.Z., Venuti, R.P., Lukas, M.A.,
Poste, G. (1992) Carvedilol: a
novel cardiovascular drug with multiple actions. Cardiovascular Drug Reviews, Vol. 10, No. 2, pp.
127-57. Neva Press, Inc.
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280.
|
Nichols, A.J.,
Ruffolo, Jr., R.R., Huffman, W.F., Poste, G. and Samanen, J. (1992)
Development of GPIIb/IIIa antagonists as antithrombotic drugs. Trends in Pharmacological
Sciences, Vol. 13, pp. 413-17.
Elsevier Science Publishers Ltd. (UK).
|
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281.
|
Fan, D., Poste, G.,
O'Brian, C.A., Seid, C., Ward, N.E., Earnest, L.E., Fidler, I.J.
(1992) Chemosensitization of
murine fibrosarcoma cells to drugs affected by the multidrug resistance
phenotype by the antidepressant trazodone: an experimental model for the reversal of intrinsic drug
resistance. International
Journal of Oncology, 1, 734-42.
National Hellenic Research Foundation, Athens, Greece.
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282.
|
Ohlstein, E.H.,
Douglas, S.A., Sung, C.P., Yue, T.L., Louden, C., Arleth, A., Poste, G.,
Ruffolo, Jr., R.R., Feuerstein, G.Z.
(1993) Carvedilol, a cardiovascular drug, prevents vascular smooth
muscle cell proliferation, migration and neointimal formation following
vascular injury. Proceedings
of the National Academy of Sciences, Vol. 90, pp. 6189-93.
|
|
283.
|
Smith, R.A.G.,
Dewdney, J.M., Fears, R., and Poste, G. (1993) Chemical derivatization of therapeutic
proteins. Trends in
Biotechnology, 11(9), pp. 397-403. Elsevier Science Publishers Ltd. (UK).
|
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284.
|
Poste, G., (1993)
Genetics, economics and ethics: the new trinity shaping the future
direction of healthcare. Campaign
for Resource. pp. 1-8,
University of Bristol, London, England.
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|
285.
|
Poste, G., (1993)
Defining a strategy for healthcare research & development in turbulent
times. Pharmaceutical Forum,
Issue 2, pp. 11-15. Amersham
International plc, Little Chalfont (UK).
|
|
286.
|
Gregoriadis, G.,
McCormack, B., Allison, A.C., Poste, G. (1993) Editors. New generation vaccines. The role of basic immunology. NATO ASI Series. Series A: Life Sciences. Vol 261. Plenum Press, New York.
|
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287.
|
Fan, D., Poste, G.,
Ruffolo, Jr., R.R., Dong, Z., Seid, C., Earnest, L.E., Campbell, T.E.,
Clyne, R.K., Belltran, P.J., Fidler, I.J. (1994) Circumvention of multidrug resistance in murine
fibrosarcoma and colon carcinoma cells by treatment with the a-adrenoceptor antagonist
furobenzazepine. International
Journal of Oncology, 4, 789-98.
|
|
288.
|
Metcalf, B., Dalton,
B.J., Poste, G. (1994)
Editors. Cellular
adhesion: molecular definition
to therapeutic potential. New
Horizons in Therapeutics, Plenum Press, New York.
|
|
289.
|
Fears, R., Suckling
K. and Poste, G. (1994) Novel
agents in the treatment of atherosclerosis. Exp. Opin. Invest. Drugs, 3, 481-91.
|
|
290.
|
Fan, D., Poste, G.,
Seid, C., Earnest, L., Bull, T., Clyne, R., and Fidler, I. (1994) Reversal of multidrug
resistance in murine fibrosarcoma cells by thioxanthene flupentixol. Investigational New Drugs,
12, 185-95.
|
|
291.
|
Fears, R. and Poste,
G. (1994) Obstacles to the
development of novel thrombolytic agents for acute myocardial infarction
therapy : is the good the enemy of the best? Fibrinolysis, 8, 214-20.
|
|
292.
|
Poste, G. (1994) R&D strategies in the
pharmaceutical industry. R&D
Efficiency, 3, 1-8.
|
|
293.
|
Fears, R., Greig,
R., Poste, G. (1994) Human
genomic research and innovative medicine. Science in Parliament, 51, 4-5.
|
|
294.
|
Poste, G. and Fears,
R. (1994) Industry's crystal ball. Science & Public
Affairs, Autumn, pp. 4-6.
|
|
295.
|
Poste, G. (1994) This house believes the NHS can no longer afford the
best medicines. The Great Oxford Debate. Pharmaceutical Times, November, pp. 26-29.
|
|
296.
|
Ruffolo, Jr., R.R.
and Poste, G. (1994) A prescription for better prescriptions : a response. Issues
in Science and Technology, Summer Supplement, p. 9.
|
|
297.
|
Ohlstein, E.H.,
Nambi, P., Douglas, S.A., Edwards, R.M., Gellai, M., Lago, A., Leber, J.D.,
Cousins, R.D., Gao, A., Frazee, J.S., Peishoff, C.E., Bean, J.W.,
Eggleston, D.S., Elshourbagy, N.A., Kumar, C., Lee, J.A., Yue, T-L.,
Louden, C., Brooks, D.P., Weinstock, J., Feuerstein, G., Poste, G.,
Ruffolo, Jr., R.R., Gleason, J.G., Elliott, J.D. (1994) SB 209670, a rationally designed
potent nonpeptide endothelin receptor antagonist. Proceedings of the National Academy of Sciences,
91, 8052-8056.
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298.
|
Gregoriadis, G.,
McCornack, B., Poste, G. (1994) Editors. Targeting of Drugs. Advances in system constructs. NATO ASI Series. Series A:
Life Sciences, Vol. 273, Plenum Press, New
York.
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299.
|
Poste, G. (1995) The study of genes and their functional regulation. Vital Speeches of the Day,
LXI (6), 165-69.
|
|
300.
|
Poste, G. (1995) Science:
The view from industry. Times Higher, Education Supplement, April 21, 1995,
p. 11.
|
|
301.
|
Feuerstein, G.Z.,
Poste, G. and Ruffolo, Jr., R.R.
(1995) Carvedilol
update III: rationale for use
in congestive heart failure. Drugs
of Today, 31, 307-26.
|
|
302.
|
Warner, M. and
Poste, G. (1995) Editors. The impact of the new genetics on
the NHS. The Cardiff Debate, Welsh
Health Planning Forum, Cardiff, Wales
|
|
303.
|
Poste, G. (1995) There was a false comfort in healthcare. Pharmaceutical Times,
October, 28-34.
|
|
304.
|
Poste, G. (1995) The case for genomic patenting. Nature, 378, 534-6.
|
|
305.
|
Fears, R and Poste
G. (1995) Enabling the future: an industry
perspective on the foresight
science policy exercise in the life sciences. Science Technology and Innovation, 8, 26-30.
|
|
306.
|
Greller, L.D.,
Tobin, F.L., Poste, G. and Wang, X.
(1995) Genetic
instability and progression interactions
in tumor dynamics. International Workshop on Information Processing in
Cells and Tissues,
pp. 569-73. The University of
Liverpool, England.
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307.
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Greller, L.D.,
Tobin, F.L. and Poste, G.
(1995) Computational
tumo heterogeneity and progression. Computational Medicine, Public Health, and
Biotechnology (Part 1).
(ed. M. Witten), 5, pp. 413-41. World Scientific Publishing Company, New Jersey.
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308.
|
Poste, G. and
McCormick D. (1995) Genomics: history and science in the making. The Biotechnology Report,
(ed. H. Price), pp. 68-9.
Campden Publishing Limited, London.
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|
309.
|
Chopra, I., Hodgson,
J. Metcalf, B., and. Poste, G.,
(1996) New approaches
to the control of infections caused by antibiotic-resistant bacteria. Journal of the American Medical
Association, 275, 401-03.
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|
310.
|
Poste, G. (1996) Is SmithKline's future in its genes? Business Week,
March 4, pp. 80-1.
|
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311
|
Fears, R. and Poste,
G. (1996) Challenges in R&D. Science and Parliamentary
Affairs, Summer Issue,
pp. 5-6.
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|
312.
|
Poste, G. (1996) An acid test for excellence. Financial Times, Invited Editorial, June 7, p.
16.
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|
313.
|
Poste, G. (1996) A strategy to promote a national asset. Financial Times, Invited
Editorial, July
19, p. 12.
|
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314.
|
Feuerstein, G.Z.,
Shusterman, N.H., Poste, G., Ruffolo, Jr., R.R. (1996) Beta-blockers and heart failure : rationale and
highlights from the carvedilol heart failure trials. Pharmaceutical News,
3, 18-23.
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|
315.
|
Greller, L.D.,
Tobin, F.L. and Poste, G.
(1996) Tumor
heterogeneity and progression : conceptual foundations for modeling. Invasion & Metastasis,
16, 177-208.
|
|
316.
|
Poste, G. (1997) Fight for your future. Pharmaceutical Times, January, p. 40.
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317.
|
Poste, G. (1997) The science of the possible. Times Higher, February, p. 12.
|
|
318.
|
Chopra, I., Hodgson,
J., Metcalf, B. and Poste, G.
(1997) The search for
antimicrobial agents effective against bacteria resistant to multiple
antibiotics.Antimicrobial Agents and Chemotherapy, 41, 497-503.
|
|
319.
|
Poste, G. (1997) Managing discontinuities in healthcare markets and
technology. Vital Speeches
of the Day, LXIII (10), 309-13.
|
|
320.
|
Poste, G. (1997) Looking back to the future: healthcare by 2022. Scrip Magazine, April, p.
34-7.
|
|
321.
|
Fears, R., Ferguson,
M.W.J., Stewart W. and Poste, G.
(1997) Life-sciences
R&D, national prosperity, and industrial competitiveness. Science, 276, 759-60.
|
|
322.
|
Poste, G., Roberts,
D. and Gentry, S. (1997) Patents, ethics and improving
healthcare. Bulletin of
Medical Ethics, 124, 29-31
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|
323.
|
Hagan, J.J.,
Middlemiss, D.N., Sharpe, P.C. and Poste, G.H. (1997)
Parkinson's disease : prospects for improved drug therapy. Trends in Pharmacological
Sciences, 18, 156-63.
|
|
324.
|
Poste, G. (1997) In praise of excellence. Financial Times, Invited Editorial, August 1, p.
16.
|
|
325.
|
Poste, G. (1997) Science, medicine and society : progress, perils,
opportunities and opponents. Vital Speeches of the Day, LXIII (24),
755-58.
|
|
326.
|
Ruffolo, Jr., R.R.,
Poste, G. and Metcalf, B.
(1997) Editors. Cell
cycle regulation. New
Horizons in
Therapeutics, Harwood Academic Publishers, The Netherlands.
|
|
327.
|
Yue, T-L, Ma, X-L,
Wang, X., Romanic, A.M., Liu, G-L, Louden, C., Gu, J-L, Kumar, S., Poste,
G. Ruffolo, Jr. and R.R. Feuerstein, G.Z. (1997)
Possible involvement of stress-activated protein kinase signaling
pathway and fas receptor expression in prevention of
ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circulation Research, 82,
166-74.
|
|
328.
|
Poste, G. (1998) Hard choices must be made for a competitive future. Research Fortnight, February
11, p. 13.
|
|
329.
|
Poste, G. (1998) New frontiers, new hurdles. The Parliament Magazine, May 4, p. 12.
|
|
330.
|
Poste, G. (1998) Molecular medicine and information-based targeted
healthcare. Nature
Biotechnology, 16 (Supplement), 19-21.
|
|
331.
|
Feuerstein, G.Z.,
Poste, G., Shusterman, N.H. and Ruffolo, Jr., R.R. (1998) The changing paradigm for pharmacotherapy of congestive
heart failure. International
Journal of Cardiovascular Medicine and Science, 1, 171-89.
|
|
332.
|
Fears,
R. and Poste, G. (1998) British science policy : reasons to
be cheerful and careful.
Science and Public Affairs, The British Association, Winter Issue.
|
|
333.
|
Poste,
G. and Fears, R. (1999) Joining up for the genome. Times Higher, Educational Supplement
19, February, pp. 40-1.
|
|
334.
|
Poste, G. and Fears,
R. (1999) Joining up for the genome. Times Higher, Educational
Supplement 19, February, pp. 40-1.
|
|
335.
|
Ruffolo, Jr., R.R.,
Feuerstein, G.Z., Hunter, A.J., Poste and G. Metcalf, B.W. (1999) Inflammatory cells and mediators in CNS diseases. New Horizons in Therapeutics,
Harwood Academic Publishers, The Netherlands.
|
|
336.
|
Poste, G. (1999) Antibiotic armageddon. Financial Times, Poste Script, March 15, p. 6.
|
|
337.
|
Fears, R. and Poste,
G. (1999) Building population genetics
resources using the U.K. NHS. Science, 284, 267-68.
|
|
338.
|
Poste, G. (1999) Not invented here : the old bromide has run its course,
probably forever. The Genesis Report/Rx, February 8(2),
8-9.
|
|
339.
|
Poste, G. and Fears,
R. (1999) How to maximise the benefits of
molecular medicine : integrated system to promote progress. UK Houses of Parliament,
Biotechnology Supplement, May 3, pp. 12-3.
|
|
340.
|
Poste, G. (1999) Making more of yourself. Financial Times, Life Sciences Supplement, 15
July, p. 6.
|
|
341.
|
Poste, G. and Fears,
R. (1999) The best ways forward. Science & Public Affairs,
Special Issue, June,
pp. 4-5.
|
|
342.
|
Fears, R. and Poste,
G. (1999) SmithKline Beecham and the future direction
of medical research. Science in Parliament, Summer Issue, 56 (3),
10-11.
|
|
343.
|
Fears, R.,
Weatherall D. and Poste, G.
(1999) The impact of
genetics on medical education and training. British Medical Bulletin, 55 (2), pp. 460-70.
|
|
344.
|
Poste, G., Bell, J.,
Davies, K., Goodfellow, P. and Hastie, N. (1999)
Editors. Impact of
genomics on healthcare. British
Medical Bulletin, 55 (2), Royal Society of Medicine Press, London, 496
pp.
|
|
345.
|
Poste, G. (1999) The new risks to scientific progress, Financial Times,
Life Sciences Supplement, 28 October, p. VII.
|
|
346.
|
Poste, G. (2000) The right treatment, for the right disease, for the
right patient. Scrip
Magazine, January, Issue 86.
|
|
347.
|
Poste, G. (2000) The First battleground for the regulation of
e.commerce. Financial Times 6
April 2000, Life Sciences Supplement IV.
|
|
348.
|
Fears, R., Roberts,
D. Poste, G. (2000) Rational
or rationed medicine? The
promise of genetics for improved clinical practice. BMJ, April 2000, pp.
933-935.
|
|
349.
|
Poste, G.
(2000) Revealing Reality
Within a Body of Imaginary Things.
Essays for Theories, Models, Methods, Approaches, Assumptions and
Findings”. Damien Hirst
Exhibition, Gagosian Gallery, New York, September 2000
|
|
350.
|
Poste, G.
(2000) R&D in the
Post-Genome World: The
Challenge of Systems Biology, Financial Times Biotechnology Survey 16 November 2000.
|
|
351.
|
Poste, G.
(2000) The Nation is Falling
Apart. Financial Times 4 December 2000
|
|
352.
|
Poste, G.
(2000) Biotechnology and the
Evolution of Molecular Medicine.
J. Biolaw and Bus. Supplement 2000, 12-16.
|
|
353.
|
Poste, G (2001) Genomics at the Cutting Edge. Financial Times 26 September 2001.
|
|
354.
|
Poste, G. (2001) Molecular diagnostics: a powerful new component of the healthcare value chain. Expert Rev. Mol. Diag. 1, 1-5.
|
|
355.
|
The Dawning Life
Sciences Defense Industry. An
Interview with George Poste.
In Vivo 2001 19 (9) 1-9.
|
|
356.
|
A Rude Awakening to
the Forces of Good and Evil.
Financial Times Biotechnology Survey. 27 November 2001.
|
|
357.
|
Poste, G. (2002)
Biotechnology and Terrorism.
Prospect. #74, 48-52.
|
|
358.
|
Poste, G.
(2002) Facing Reality in
Preparing for Biological Warfare.
Health Affairs 21.
|
|
359.
|
Poste, G. (2002)
Biotechnology, Bioterrorism and Biosecurity. Drug Discovery World. Summer 2002, pp. 9-21.
|
|